Lorne Golub Selected Research

tetracycline CMT-3

1/2015	Impact of chemically-modified tetracycline 3 on intertwined physiological, biochemical, and inflammatory networks in porcine sepsis/ARDS.
4/2012	Chemically modified tetracycline 3 prevents acute respiratory distress syndrome in a porcine model of sepsis + ischemia/reperfusion-induced lung injury.
10/2005	Chemically modified tetracycline prevents the development of septic shock and acute respiratory distress syndrome in a clinically applicable porcine model.

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Lorne Golub Research Topics

Disease

3	Inflammation (Inflammations) 01/2015 - 10/2005
3	Sepsis (Septicemia) 01/2015 - 10/2005
2	Ischemia 01/2015 - 04/2012
2	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 04/2012 - 10/2005
1	Respiratory Insufficiency (Respiratory Failure) 01/2015
1	Acidosis 01/2015
1	Acute Kidney Injury (Acute Renal Failure) 01/2015
1	Lung Injury 04/2012
1	Septic Shock (Toxic Shock Syndrome) 10/2005
1	Thrombosis (Thrombus) 10/2005
1	Reperfusion Injury 10/2005

Drug/Important Bio-Agent (IBA)

3	tetracycline CMT-3IBA 01/2015 - 10/2005
3	Tetracycline (Achromycin)FDA LinkGeneric 01/2015 - 10/2005
2	Peptide Hydrolases (Proteases)FDA Link 04/2012 - 10/2005
2	CytokinesIBA 04/2012 - 10/2005
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 04/2012
1	Carboxymethylcellulose Sodium (Polycell)FDA Link 04/2012
1	pyridinolineIBA 10/2005
1	OsteocalcinIBA 10/2005
1	GelatinasesIBA 10/2005
1	Leukocyte Elastase (Neutrophil Elastase)IBA 10/2005
1	Matrix Metalloproteinases (MMPs)IBA 10/2005
1	Collagen Type I (Type I Collagen)IBA 10/2005

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 04/2012
1	Laparotomy 10/2005